If you have started the shot and something in you has gone quiet — the music does not hit the same, the wine does not taste the same, the walk with your dog is a task instead of a joy — you are not imagining it.

There is a name for what is happening. There is a mechanism. And there are five specific questions to bring to your next appointment that will get you a real answer instead of a two-minute prescription refill.

I wrote them because my inbox is full of people who tried to describe this to their clinician and got told it was stress, hormones, or aging. It is none of those. It is pharmacology, and it is worth asking about out loud.

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